28 research outputs found

    DEVELOPMENT OF FORECASTING AND SCHEDULING METHODS AND DATA ANALYTICS BASED CONTROLS FOR SMART LOADS IN RESIDENTIAL BUILDINGS.

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    DEVELOPMENT OF FORECASTING AND SCHEDULING METHODS AND DATA ANALYTICS BASED CONTROLS FOR SMART LOADS IN RESIDENTIAL BUILDINGS

    Campylobacter infection and household factors are associated with childhood growth in urban Bangladesh : an analysis of the MAL-ED study

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    The dual burden of enteric infection and childhood malnutrition continues to be a global health concern and a leading cause of morbidity and death among children. Campylobacter infection, in particular, is highly prevalent in low- and middle-income countries, including Bangladesh. We examined longitudinal data to evaluate the trajectories of change in child growth, and to identify associations with Campylobacter infection and household factors. The study analyzed data from 265 children participating in the MAL-ED Study in Mirpur, Bangladesh. We applied latent growth curve modelling to evaluate the trajectories of change in children’s height, as measured by length-for-age z-score (LAZ), from age 0–24 months. Asymptomatic and symptomatic Campylobacter infections were included as 3- and 6-month lagged time-varying covariates, while household risk factors were included as time-invariant covariates. Maternal height and birth order were positively associated with LAZ at birth. An inverse association was found between increasing age and LAZ. Campylobacter infection prevalence increased with age, with over 70% of children 18–24 months of age testing positive for infection. In the final model, Campylobacter infection in the preceding 3-month interval was negatively associated with LAZ at 12, 15, and 18 months of age; similarly, infection in the preceding 6-month interval was negatively associated with LAZ at 15, 18, and 21 months of age. Duration of antibiotic use and access to treated drinking water were negatively associated with Campylobacter infection, with the strength of the latter effect increasing with children’s age. Campylobacter infection had a significant negative effect on child’s growth and this effect was most powerful between 12 and 21 months. The treatment of drinking water and increased antibiotic use have a positive indirect effect on linear child growth trajectory, acting via their association with Campylobacter infection

    COVID-19 among staff and their family members of a healthcare research institution in Bangladesh between March 2020 and April 2021 : a test-negative case–control study

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    Objective To identify factors associated with COVID- 19 positivity among staff and their family members of icddr,b, a health research institute located in Bangladesh. Setting Dhaka, Bangladesh. Participants A total of 4295 symptomatic people were tested for SARS-CoV-2 by reverse-transcription PCR between 19 March 2020 and 15 April 2021. Multivariable logistic regression was done to identify the factors associated with COVID- 19 positivity by contrasting test positives with test negatives. Result Forty-three per cent of the participants were tested positive for SARS-CoV-2. The median age was high in positive cases (37 years vs 34 years). Among the positive cases, 97% were recovered, 2.1% had reinfections, 24 died and 41 were active cases as of 15 April 2021. Multivariable regression analysis showed that age more than 60 years (adjusted OR (aOR)=2.1, 95% CI 1.3 to 3.3; pwere tested negative. Conclusions The study findings suggest that older age, fever, cough and anosmia were associated with COVID- 19 among the study participants.publishedVersionPeer reviewe

    Causal Pathways from Enteropathogens to Environmental Enteropathy: Findings from the MAL-ED Birth Cohort Study

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    Background Environmental enteropathy (EE), the adverse impact of frequent and numerous enteric infections on the gut resulting in a state of persistent immune activation and altered permeability, has been proposed as a key determinant of growth failure in children in low- and middle-income populations. A theory-driven systems model to critically evaluate pathways through which enteropathogens, gut permeability, and intestinal and systemic inflammation affect child growth was conducted within the framework of the Etiology, Risk Factors and Interactions of Enteric Infections and Malnutrition and the Consequences for Child Health and Development (MAL-ED) birth cohort study that included children from eight countries. Methods Non-diarrheal stool samples (N = 22,846) from 1253 children from multiple sites were evaluated for a panel of 40 enteropathogens and fecal concentrations of myeloperoxidase, alpha-1-antitrypsin, and neopterin. Among these same children, urinary lactulose:mannitol (L:M) (N = 6363) and plasma alpha-1-acid glycoprotein (AGP) (N = 2797) were also measured. The temporal sampling design was used to create a directed acyclic graph of proposed mechanistic pathways between enteropathogen detection in non-diarrheal stools, biomarkers of intestinal permeability and inflammation, systemic inflammation and change in length- and weight- for age in children 0–2 years of age. Findings Children in these populations had frequent enteric infections and high levels of both intestinal and systemic inflammation. Higher burdens of enteropathogens, especially those categorized as being enteroinvasive or causing mucosal disruption, were associated with elevated biomarker concentrations of gut and systemic inflammation and, via these associations, indirectly associated with both reduced linear and ponderal growth. Evidence for the association with reduced linear growth was stronger for systemic inflammation than for gut inflammation; the opposite was true of reduced ponderal growth. Although Giardia was associated with reduced growth, the association was not mediated by any of the biomarkers evaluated. Interpretation The large quantity of empirical evidence contributing to this analysis supports the conceptual model of EE. The effects of EE on growth faltering in young children were small, but multiple mechanistic pathways underlying the attribution of growth failure to asymptomatic enteric infections had statistical support in the analysis. The strongest evidence for EE was the association between enteropathogens and linear growth mediated through systemic inflammation

    Early life child micronutrient status, maternal reasoning, and a nurturing household environment have persistent influences on child cognitive development at age 5 years: Results from MAL-ED

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    Background: Child cognitive development is influenced by early-life insults and protective factors. To what extent these factors have a long-term legacy on child development and hence fulfillment of cognitive potential is unknown. Objective: The aim of this study was to examine the relation between early-life factors (birth to 2 y) and cognitive development at 5 y. Methods: Observational follow-up visits were made of children at 5 y, previously enrolled in the community-based MAL-ED longitudinal cohort. The burden of enteropathogens, prevalence of illness, complementary diet intake, micronutrient status, and household and maternal factors from birth to 2 y were extensively measured and their relation with the Wechsler Preschool Primary Scales of Intelligence at 5 y was examined through use of linear regression. Results: Cognitive T-scores from 813 of 1198 (68%) children were examined and 5 variables had significant associations in multivariable models: mean child plasma transferrin receptor concentration (β: −1.81, 95% CI: −2.75, −0.86), number of years of maternal education (β: 0.27, 95% CI: 0.08, 0.45), maternal cognitive reasoning score (β: 0.09, 95% CI: 0.03, 0.15), household assets score (β: 0.64, 95% CI: 0.24, 1.04), and HOME child cleanliness factor (β: 0.60, 95% CI: 0.05, 1.15). In multivariable models, the mean rate of enteropathogen detections, burden of illness, and complementary food intakes between birth and 2 y were not significantly related to 5-y cognition. Conclusions: A nurturing home context in terms of a healthy/clean environment and household wealth, provision of adequate micronutrients, maternal education, and cognitive reasoning have a strong and persistent influence on child cognitive development. Efforts addressing aspects of poverty around micronutrient status, nurturing caregiving, and enabling home environments are likely to have lasting positive impacts on child cognitive development.publishedVersio

    Direct Torque Control of AC Machine Drives

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    Field oriented control (FOC) and direct torque control (DTC) are the two most important control strategies for modern advanced machine drives. Field oriented control (FOC) has been widely used as the industrial motor drives. The direct torque control has been recently developed by Takashi and has shown great potential in machine drive applications. This thesis discusses the performances of direct torque control on AC machine drives including the industrial workhorse induction machines (IM) and permanent magnet synchronous machines (PMSM). Both of the IM and PMSM dynamics models are derived in details in the thesis. By applying nonlinear filtering techniques, the sensorless direct torque control of AC machine drives are studied. MATLAB simulations have shown the efficacy and superior performance of the resilient extended Kalman filter over the traditional extended Kalman filter for direct torque control applications

    Month-Wise Investigation on Residential Load Consumption Impact during COVID-19 Period on Distribution Transformer and Practical Mitigation Solution

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    This paper investigates the month-wise impact of COVID-19 conditions on residential load due to people’s presence at home during office hours in Memphis city, Tennessee, USA. The energy consumption patterns of four consumers are analyzed based on the data available from pre-COVID to continuing COVID-19 situations. It is observed that the energy consumptions from April 2020 to June 2021 for all families have increased during office hours than that of pre-COVID months. Therefore, the impacts of the increased loads on distribution transformer are analyzed in terms of hottest spot, top-oil temperature, and loss of transformer life. Moreover, an experimental setup is made to produce the harmonics in currents of non-linear residential load which has detrimental effects on temperature rise of distribution transformer. In addition, this work proposes implementation of harmonic filter at the load side considering the impact of harmonics produced by loads to reduce the temperature rise due to the increased load consumption and presence of harmonics in currents produced by the load. The rise in temperatures and the loss of life of distribution transformer with and without the proposed solutions are simulated in MATLAB to show the efficacy of the proposed solution. Moreover, cost value analysis among different methods, which can be implemented to reduce the adverse impact on distribution transformer, are provided to rank the available methods

    Analysis of COVID-19 effect on residential loads and distribution transformers

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    This paper analyzes the impact of COVID-19 pandemic situation on residential loads and local distribution transformer. The transformers’ operating conditions in terms of hottest winding temperature, top oil transformer, loss of life (%LOL) are analyzed considering different loads and harmonics content in the transformer currents. Based on these analyses, safe operating conditions of transformer are derived. Six types of consumers having different consumption patterns and different type of residential loads are considered for the analysis. In order to mitigate the adverse impacts of COVID-19 on loads and distribution transformer, the use of behind-the-meter (BTM) photovoltaic (PV) source, battery energy storage and electric vehicle, load scheduling, and less utilization of loads that have distortion factors during office hours are proposed. A performance comparison has been made without and with considering the proposed BTM solution, load scheduling and loads having distortion factors. Simulation results show that, due to lockdown situation of COVID-19 issue, the residential loads consumptions increase during office hours and hence the local distribution transformer gets affected. Also, the proposed BTM solution, load scheduling and less utilization of loads having harmonic distortion can cope up with the increased energy consumptions during office hours

    Evaluation of transfer factors of 226Ra, 232Th, and 40K radionuclides from soil to grass and mango in the northern region of Bangladesh

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    Bangladesh is a rapidly developing country, which is vulnerable to various types of pollution due to the large-scale industrial and associated human activities that might potentially affect the locally harvested foodstuffs. Therefore, the transfer factor is an essential tool to assess the safety of foodstuffs due to the presence of natural radioactivity in environmental matrix and/or strata. This is a first study of its kind conducted in a well-known region for mango farming in Bangladesh, measuring the uptake of naturally occurring radioactive materials (NORMs) by grass and mango from soil to assess the ingestion doses to humans. The HPGe gamma-ray detector was used to determine the concentrations of NORMs in samples of soil (20), grass (10), and mango (10), which were then used to calculate the transfer factors of soil to grass and soil to mango. Average activity concentrations of 226Ra, 232Th, and 40K in associated soil samples (47.27 ± 4.10, 64.49 ± 4.32, 421.60 ± 28.85) of mango and 226Ra and 232Th in associated soil samples (45.07 ± 3.93, 52.17 ± 3.95) of grass were found to exceed the world average values. The average transfer factors (TFs) for mango were obtained in the order of 40K(0.80) > 226Ra (0.61) > 232Th (0.31), and for grass, it shows the order of 40K (0.78) > 232Th (0.64) > 226Ra (0.56). However, a few values (3 mango samples and 3 grass samples) of the estimated TFs exceeded the recommended limits. Moreover, Bangladesh lacks the transfer factors for most of the food crops; therefore, calculation of TFs in the major agricultural products is required all over Bangladesh, especially the foodstuffs produced near the Rooppur Nuclear Power Plant, which is scheduled to be commissioned in 2023
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